Bloodshot's nanites made him a nearly unstoppable killing machine. His enhanced strength, speed, endurance, and healing made him the perfect weapon, and he served his masters at Project Rising Spirit - a private contractor trafficking in violence - very well.

Now, Bloodshot is a shadow of his former self. He lives in self-imposed exile, reeling from the consequences of his past life and the recent events that nearly drove him mad. But when a rash of shootings by gunmen who appear to look just like Bloodshot begin, his guilt will send him on a mission to stop the killers, even if it means diving headlong into the violence that nearly destroyed him.